Yayınlanmış 1 Ocak 2015
| Sürüm v1
Dergi makalesi
Açık
Image-derived and arterial blood sampled input functions for quantitative PET imaging of the angiotensin II subtype 1 receptor in the kidney
Yazarlar/Oluşturanlar
- 1. Johns Hopkins Sch Med, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA
Açıklama
Purpose: The radioligand C-11-KR31173 has been introduced for positron emission tomography (PET) imaging of the angiotensin II subtype 1 receptor in the kidney in vivo. To study the biokinetics of C-11-KR31173 with a compartmental model, the input function is needed. Collection and analysis of arterial blood samples are the established approach to obtain the input function but they are not feasible in patients with renal diseases. The goal of this study was to develop a quantitative technique that can provide an accurate image-derived input function (ID-IF) to replace the conventional invasive arterial sampling and test the method in pigs with the goal of translation into human studies.
Dosyalar
bib-04290be6-0df0-4b78-a3e7-239bb2dec673.txt
Dosyalar
(262 Bytes)
| Ad | Boyut | Hepisini indir |
|---|---|---|
|
md5:f6ed5a586e107aacf1971bfa03a34428
|
262 Bytes | Ön İzleme İndir |