Yayınlanmış 1 Ocak 2017 | Sürüm v1

Impact of Neuro-Behcet Disease Immunoglobulin G on Neuronal Apoptosis

  • 1. Istanbul Univ, Aziz Sancar Inst Expt Med Res, Dept Neurosci, Istanbul, Turkey
  • 2. Istanbul Univ, Aziz Sancar Inst Expt Med Res, Dept Mol Med, Istanbul, Turkey
  • 3. Istanbul Univ, Sch Med, Dept Neurol, Istanbul, Turkey

Açıklama

Introduction: Parenchymal neuro-Behcet disease (NBD) is encountered in 5%-15% of Behcet disease (BD) patients and is characterized by inflammation of the brainstem and diencephalon structures. Neuronal apoptosis has been shown to participate in neuronal cell loss. Anti-neuronal antibodies have been identified in NBD patients. However, the pathogenic properties of these antibodies have not been studied.

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