Yayınlanmış 1 Ocak 2003
| Sürüm v1
Dergi makalesi
Açık
Electronic-Topological Study of Structurally Diverse Cyclooxygenase-2 Inhibitors
Yazarlar/Oluşturanlar
- 1. Gebze Inst Technol, TR-41400 Gebze, Turkey
Açıklama
A large series of cyclooxygenase-2 (COX-2) inhibitors with diverse skeletons were investigated by means of the Electronic-Topological Method. A system for the COX-2 inhibitor activity prognostication was built with 6 pharmacophores and 6 anti-pharmacophores. The forecasting ability of the system was also tested on different structures, which differ from those that characterize the series studied.
Dosyalar
bib-915c668f-c09a-4669-9353-6730650e700a.txt
Dosyalar
(186 Bytes)
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186 Bytes | Ön İzleme İndir |