Yayınlanmış 1 Ocak 2018
| Sürüm v1
Dergi makalesi
Açık
p38 Mitogen-Activated Protein Kinase is Involved in the Pathogenesis of Endometriosis by Modulating Inflammation, but not Cell Survival
Yazarlar/Oluşturanlar
- 1. Univ S Florida, Dept Obstet & Gynecol, Morsani Coll Med, 4202 E Fowler Ave, Tampa, FL 33620 USA
- 2. Yale Univ, Sch Med, Dept Obstet Gynecol & Reprod Sci, New Haven, CT USA
Açıklama
Background: Local pro-inflammatory environment and enhanced cell survival contribute to the endometriosis development. A serine/threonine kinase p38 mitogen-activated protein kinase (MAPK) mediates intracellular signaling of cytokine production, cell proliferation, and apoptosis in different cell types. The current study compares p38 MAPK activity in normal endometrium and endometriosis, and assesses role(s) of p38 MAPK on cytokine production and cell survival in endometriosis.
Dosyalar
bib-e2c6e95a-6112-40ac-91c4-fe0b99bb07c4.txt
Dosyalar
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