Yayınlanmış 1 Ocak 2013 | Sürüm v1

GC-MS Investigation and Acetylcholinesterase Inhibitory Activity of Galanthus rizehensis

  • 1. Ege Univ, Fac Pharm, Dept Pharmacognosy, TR-35100 Izmir, Turkey
  • 2. Univ Barcelona, Fac Farm, Dept Prod Nat Biol Vegetal & Edafol, E-08028 Barcelona, Spain
  • 3. AgroBio Inst, Sofia 1164, Bulgaria

Açıklama

GC-MS (gas chromatography-mass spectrometry) analyses of alkaloids in the aerial parts and bulbs of Galanthus rizehensis Stern (Amaryllidaceae), collected during two different vegetation periods, was performed. Twenty three alkaloids were identified in four different alkaloid extracts. Acetylcholinesterase (AChE) inhibitory activities of the alkaloid extracts were tested. Both the highest alkaloid diversity and the most potent inhibitory activity (IC50 12.94 mu g/ml) were obtained in extracts from the bulbs of G. rizehensis collected during the fruiting period.

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