Yayınlanmış 1 Ocak 2013
| Sürüm v1
Dergi makalesi
Açık
The roles of epigenetic modifications of proapoptotic BID and BIM genes in imatinib-resistant chronic myeloid leukemia cells
Yazarlar/Oluşturanlar
- 1. Hacettepe Univ, Dept Basic Oncol, Inst Oncol, TR-06100 Ankara, Turkey
- 2. Ankara Univ, Fac Med, Dept Med Biol, TR-06100 Ankara, Turkey
- 3. Izmir Inst Technol, Fac Sci, Dept Mol Biol & Genet, Izmir, Turkey
Açıklama
In chronic myeloid leukemia (CML), epigenetic modifications such as promoter hypermethylation and inactive histone modification are known mechanisms of drug resistance. In our study, we investigated the roles of promoter hypermethylation of BIM and BID genes and H3K27me3 histone modification on imatinib resistance.
Dosyalar
bib-4b443ece-1b1b-4dc6-a0a8-973e954ec987.txt
Dosyalar
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